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William Hogan MD, MS
William Hogan, MD, MS

William Hogan, MD, MS

Mary T. and Ted D. Kellner Chair of Data Science; Director, Data Science Institute; Professor, Data Science Institute; Associate Director for Data Science, Mellowes Center for Genomic and Precision Medicine

Locations

  • DSI
  • TBRC C4166

    Secondary Appointment: Department of Medicine

Contact Information

Education

BS, Pennsylvania State University
MD, Medicine, Jefferson Medical College
MS, Intelligent Systems, University of Pittsburg

Biography

Dr. Hogan is professor and the founding director of the Data Science Institute. He has over 20 years experience in biomedical data science and informatics, including numerous leadership roles and accomplishments in building large-scale infrastructure, creating and implementing public health surveillance systems, developing and disseminating data standards, designing and validating artificial intelligence models, and innovating analysis methods. He has also created graduate programs in biomedical data science and informatics from the ground up, with their PhD graduates moving on to post-doctoral research fellowships and faculty positions at multiple institutions. He has served as research mentor to over 20 junior faculty, post-doctoral research fellows, and MS and PhD students. Over the years, he has been principal investigator or co-investigator on over $100M in grant funding, including major infrastructure grants that include as a core component the transformation of electronic health record data into a research-ready resource for observational and comparative effectiveness studies, pragmatic trials, disease surveillance, and cohort discovery for enrollment in trials. He has authored over 150 peer-reviewed publications describing this work. His core area of interest is biomedical ontology, or how to represent the types of things that are objects of study in healthcare and biomedical science in order to ensure that data are reusable and that information systems are interoperable. He is the creator and lead curator of three, major ontologies in the Open Biological and Biomedical Ontology (OBO) Foundry: the Drug Ontology, the Ontology of Medically Relevant Social Entities, and the Apollo-SV ontology. All three ontologies rank in the top 20% of OBO ontologies in terms of re-use by other OBO ontologies. He serves on the OBO Foundry Operations Committee and its Editorial Working Group.

Publications

  • (Li P, Spector E, Alkhuzam K, Patel R, Donahoo WT, Bost S, Lyu T, Wu Y, Hogan W, Prosperi M, Dixon BE, Dabelea D, Utidjian LH, Crume TL, Thorpe L, Liese AD, Schatz DA, Atkinson MA, Haller MJ, Shenkman EA, Guo Y, Bian J, Shao H.) Diabetes Obes Metab. 2025 Jan;27(1):102-110 PMID: 39344840 PMCID: PMC11620941 SCOPUS ID: 2-s2.0-85205514261 09/30/2024

  • (Nagarajan R, Kondo M, Salas F, Sezgin E, Yao Y, Klotzman V, Godambe SA, Khan N, Limon A, Stephenson G, Taraman S, Walton N, Ehwerhemuepha L, Pandit J, Pandita D, Weiss M, Golden C, Gold A, Henderson J, Shippy A, Celi LA, Hogan WR, Oermann EK, Sanger T, Martel S.) J Med Internet Res. 2024 Nov 14;26:e64226 PMID: 39541580 PMCID: PMC11605263 SCOPUS ID: 2-s2.0-85209360841 11/14/2024

  • (Duncan WD, Diller M, Dooley D, Hogan WR, Beverley J.) J Biomed Semantics. 2024 Aug 20;15(1):15 PMID: 39160586 PMCID: PMC11334599 SCOPUS ID: 2-s2.0-85201569755 08/20/2024

  • (Loftus TJ, Balch JA, Abbott KL, Hu D, Ruppert MM, Shickel B, Ozrazgat-Baslanti T, Efron PA, Tighe PJ, Hogan WR, Rashidi P, Cardel MI, Upchurch GR Jr, Bihorac A.) PLOS Digit Health. 2024 Aug;3(8):e0000561 PMID: 39178307 PMCID: PMC11343451 08/23/2024

  • (Loftus TJ, Ruppert MM, Shickel B, Ozrazgat-Baslanti T, Balch JA, Abbott KL, Hu D, Javed A, Madbak F, Guirgis F, Skarupa D, Efron PA, Tighe PJ, Hogan WR, Rashidi P, Upchurch GR Jr, Bihorac A.) Ann Surg Open. 2024 Jun;5(2):e429 PMID: 38911666 PMCID: PMC11191932 06/24/2024

  • (Wagner MM, Hogan WR, Levander JD, Diller M.) J Biomed Inform. 2024 Jun;154:104647 PMID: 38692465 PMCID: PMC11250896 SCOPUS ID: 2-s2.0-85192218312 05/02/2024

  • (Yu Z, Peng C, Yang X, Dang C, Adekkanattu P, Gopal Patra B, Peng Y, Pathak J, Wilson DL, Chang CY, Lo-Ciganic WH, George TJ, Hogan WR, Guo Y, Bian J, Wu Y.) J Biomed Inform. 2024 May;153:104642 PMID: 38621641 PMCID: PMC11141428 SCOPUS ID: 2-s2.0-85190333397 04/16/2024

  • (Lemas DJ, Du X, Rouhizadeh M, Lewis B, Frank S, Wright L, Spirache A, Gonzalez L, Cheves R, Magalhães M, Zapata R, Reddy R, Xu K, Parker L, Harle C, Young B, Louis-Jaques A, Zhang B, Thompson L, Hogan WR, Modave F.) Sci Rep. 2024 Apr 03;14(1):7831 PMID: 38570569 PMCID: PMC10991582 SCOPUS ID: 2-s2.0-85189809672 04/04/2024

  • (Hastings J, Zhang L, Schenk P, West R, Gehrke B, Hogan WR, Chorpita B, Johnston M, Marques MM, Webb TL, Baird HM, Crombez G, Michie S.) Wellcome Open Res. 2024;9:656 PMID: 39664869 PMCID: PMC11632217 12/12/2024

  • (Varma JK, Zang C, Carton TW, Block JP, Khullar DJ, Zhang Y, Weiner MG, Rothman RL, Schenck EJ, Xu Z, Lyman K, Bian J, Xu J, Shenkman EA, Maughan C, Castro-Baucom L, O'Brien L, Wang F, Kaushal R, RECOVER Consortium.) PLoS One. 2024;19(6):e0282451 PMID: 38843159 PMCID: PMC11156291 SCOPUS ID: 2-s2.0-85195439417 06/06/2024

  • (Ozrazgat-Baslanti T, Ren Y, Adiyeke E, Islam R, Hashemighouchani H, Ruppert M, Miao S, Loftus T, Johnson-Mann C, Madushani RWMA, Shenkman EA, Hogan W, Segal MS, Lipori G, Bihorac A, Hobson C.) PLoS One. 2024;19(4):e0299332 PMID: 38652731 PMCID: PMC11037544 SCOPUS ID: 2-s2.0-85191405922 04/23/2024

  • (Chen A, Zhao Y, Zheng Y, Hu H, Hu X, Fishe JN, Hogan WR, Shenkman EA, Guo Y, Bian J.) Informatics. March 2024;11(1) SCOPUS ID: 2-s2.0-85188969915 03/01/2024

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