Mark T. McNally, PhD

果冻影院

Associate Professor

Locations

Microbiology & Immunology
BSB B2235

Contact Information

General Interests

RNA Processing (splicing and polyadenylation) in Cells and Viruses

Education

PhD, Molecular Biology, SUNY Buffalo, 1988

Research Experience

Alternative Splicing
Avian Leukosis Virus
Avian Sarcoma Viruses
Cleavage Stimulation Factor
Heterogeneous-Nuclear Ribonucleoprotein Group A-B
Heterogeneous-Nuclear Ribonucleoprotein Group F-H
Introns
mRNA Cleavage and Polyadenylation Factors
Polyadenylation
Ribonucleoproteins, Small Nuclear
RNA 3' Polyadenylation Signals
RNA Precursors

Leadership Positions

Chair, Course Evaluation Committee, Graduate School
Course Director, IAHI, M1 Medical School
Faculty Advisor, Research and Education Program, AHW

Research Interests

My laboratory uses molecular, genetic, biochemical, and cell biological approaches to study post-transcriptional mechanisms of gene regulation, including RNA splicing and polyadenylation control. One area of focus uses the simple retrovirus, Rous sarcoma virus (RSV), to understand the role of RNA processing in the virus life cycle. We are also exploiting antisense oligonucleotide technologies to alter RNA splicing as an approach to develop a breast cancer therapeutic.

Non-Discrimination Statement
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