果冻影院

果冻影院
果冻影院 果冻影院
Research Group Lab Hall
Pharmacology and Toxicology
Todd Miller, PhD

Todd W. Miller, PhD

WBCS Professor of Breast Cancer Research and Professor of Pharmacology and Toxicology

Locations

  • Basic Science Building (BSB) B6740
  • 8701 Watertown Plank Rd.
    BSB ROOM 6740 PH096
    Milwaukee, WI 53226

Contact Information

Education

PhD, Biomedical Sciences, University of Albany, Albany, NY, 2004
BS, Physiology and Neurobiology, University of Connecticut, Storrs, CT, 1998
Post-doctoral Research Fellow, Dept. of Medicine, Vanderbilt University (Nashville, TN), 2004-2009

Biography

Dr. Miller was recruited to the 果冻影院 in 2023 as a professor of pharmacology & toxicology and pathology, and to serve as Co-Leader of the Discovery & Developmental Therapeutics Research Program at the 果冻影院 Cancer Center. He leads a translational research laboratory focused on the development of improved treatment strategies for breast cancer and mechanisms of drug resistance.

Prior to joining 果冻影院, Dr. Miller led a research laboratory at the Dartmouth Cancer Center within the Geisel School of Medicine at Dartmouth College for 11 years. He served as Co-Director of the Dartmouth Cancer Center Research Program in Cancer Signaling, Genomes, & Networks (2019-2023), Scientific Director of the Comprehensive Breast Program (2013-2023), and Professor of Molecular & Systems Biology. He also directed the PhD Program in Experimental & Molecular Medicine (2019-2020) and led the establishment of a new Cancer Biology Graduate Program (2020).

Cancer biology and mechanisms of drug resistance has been the main focus of his work for over 18 years. His data provide some of the most frequently cited evidence to support clinical development of therapeutics such as PI3K, AKT, mTOR, and CDK4/6 inhibitors, and stronger anti-estrogens for breast cancer. His expertise in translational cancer research positions him to partner with oncologists to effectively carry promising findings from experimental models to the clinic. Through scientist-clinician partnerships, they conduct early-phase clinical studies to test novel therapies and develop biomarkers.

Please see the for additional information about our group and research.

Honors and Awards

1995-1998 Honors Program (every semester, Clemson University 95-96, University of Connecticut 96-98)
1995-1998 Dean鈥檚 List (every semester, Clemson University 95-96, University of Connecticut 96-98)
1997 Vice President of chapter of National Honor Fraternity (University of Connecticut)
1997, 1998 National Dean鈥檚 List (University of Connecticut)
1997, 1998 New England Scholar (University of Connecticut)
1997 Golden Key Honor Society
1998 University of Connecticut Honors Scholar
2003 Society for Neuroscience travel award to present at International Brain Research Organization World Congress
2004 American Society of Gene Therapy travel award to present at annual meeting
2006 Accepted participant in the AACR Pathobiology of Cancer Workshop
2006 First place poster award at Vanderbilt-Ingram Cancer Center Annual Retreat
2007 Susan G. Komen Breast Cancer Foundation Scholar-in-Training travel award to present at AACR Special Conference on Breast Cancer
2008 Novartis Oncology Basic Science Scholars travel award to present at San Antonio Breast Cancer Symposium
2009 Susan G. Komen for the Cure Scholar-in-Training travel award to present at AACR Advances in Breast Cancer Research Special Conference
2009 Susan G. Komen for the Cure Scholar-in-Training travel award to present at San Antonio Breast Cancer Symposium
2012 Norris Cotton Cancer Center Award for Excellence in Translational Research (for co-catalyzing and acquiring extramural funding for clinical trials)
2014 Norris Cotton Cancer Center Award for Excellence in Genomic Medicine (for co-founding, co-developing, and co-directing Molecular Tumor Board)
2016 Jon Shevell Young Scientist Travel Scholarship from Susan G. Komen to present at San Antonio Breast Cancer Symposium
2017 Jon Shevell Young Scientist Travel Scholarship from Susan G. Komen to present at National Cancer Research Institute Cancer Conference
2018 Friends Research Scholar award (Norris Cotton Cancer Center)
2018 Jon Shevell Young Scientist Travel Scholarship from Susan G. Komen to present at San Antonio Breast Cancer Symposium
2022 Faculty Mentoring Award, Guarini School of Graduate and Advanced Studies, Dartmouth College

Research Interests

1) Mechanisms of resistance to endocrine and targeted therapies in breast cancer

2) Biomarkers of response/resistance to anti-cancer therapeutics

Publications

  • (Bagheri M, Mohamed GA, Mohamed Saleem MA, Ognjenovic NB, Lu H, Kolling FW, Wilkins OM, Das S, LaCroix IS, Nagaraj SH, Muller KE, Gerber SA, Miller TW, Pattabiraman DR.) Cell Rep Med. 2024 Apr 16;5(4):101504 PMID: 38593809 PMCID: PMC11031425 04/10/2024

  • (Bagheri M, Lee MK, Muller KE, Miller TW, Pattabiraman DR, Christensen BC.) Epigenomics. 2024 Mar;16(5):293-308 PMID: 38356412 PMCID: PMC10910603 02/15/2024

  • (Romo BA, Karakyriakou B, Cressey L, Brauer BL, Yang H, Warren A, Johnson AL, Kettenbach AN, Miller TW.) Cancers (Basel). 2024 Feb 20;16(5) PMID: 38473207 PMCID: PMC10930732 03/13/2024

  • (Traphagen NA, Schwartz GN, Tau S, Roberts AM, Jiang A, Hosford SR, Marotti JD, Goen AE, Romo BA, Johnson AL, Duffy EK, Demidenko E, Heverly P, Mosesson Y, Soucy SM, Kolling F, Miller TW.) Clin Cancer Res. 2023 Sep 15;29(18):3717-3728 PMID: 37439680 PMCID: PMC10528687 07/13/2023

  • (Schwartz GN, Kaufman PA, Giridhar KV, Marotti JD, Chamberlin MD, Arrick BA, Makari-Judson G, Goetz MP, Soucy SM, Kolling F, Demidenko E, Miller TW.) Clin Cancer Res. 2023 Aug 01;29(15):2767-2773 PMID: 37260292 PMCID: PMC10688025 06/01/2023

  • (Bagheri M, Lee MK, Muller KE, Miller TW, Pattabiraman DR, Christensen BC.) bioRxiv. 2023 Jun 10 PMID: 37333096 PMCID: PMC10274899 06/19/2023

  • (Bagheri M, Aisha Mohamed G, Mohamed Saleem MA, Ognjenovic NB, Lu H, Kolling FW, Wilkins OM, Das S, La Croix IS, Nagaraj SH, Muller KE, Gerber SA, Miller TW, Pattabiraman DR.) bioRxiv. 2023 Apr 21 PMID: 37131809 PMCID: PMC10153261 05/03/2023

  • (Traphagen NA, Schwartz GN, Tau S, Jiang A, Hosford SR, Goen AE, Roberts AM, Romo BA, Johnson AL, Duffy EK, Demidenko E, Heverly P, Mosesson Y, Soucy SM, Kolling F, Miller TW.) bioRxiv. 2023 Mar 17 PMID: 36993590 PMCID: PMC10055145 03/31/2023

  • (Tau S, Miller TW.) Clin Cancer Res. 2023 Mar 14;29(6):989-990 PMID: 36626159 PMCID: PMC10023365 01/11/2023

  • (Tau S, Miller TW.) Cancer Metastasis Rev. 2023 Mar;42(1):87-98 PMID: 36696004 PMCID: PMC10233409 01/26/2023

  • (Phillips JD, Pooler DB, Ness DB, Fay K, Tau S, Demidenko E, Hampsch RA, Lewis LD, Miller TW.) Br J Clin Pharmacol. 2023 Mar;89(3):1027-1035 PMID: 36164710 PMCID: PMC9931625 09/28/2022

  • (Traphagen NA, Hosford SR, Jiang A, Marotti JD, Brauer BL, Demidenko E, Miller TW.) Oncogene. 2021 May;40(19):3408-3421 PMID: 33875787 PMCID: PMC8122072 04/21/2021

Publications of from the