Ivor Benjamin Lab
Dr. Benjamin has been a champion by providing leadership to broaden the global reach of biomedical research in efforts to reduce death and disability from cardiovascular diseases, stroke and other brain disorders.
He is a primary investigator for other major cardiovascular research projects including a $4 million award funded by the Advancing a Healthier Wisconsin Endowment. Recently, he completed his term as president of the Association of University Cardiologists and is now serving a year-long tenure as the American Heart Association’s 82nd president.
CVC In The News
Watch Dr. Benjamin introduce new functionality that provides the ability for people to access health data from an on-demand Electrocardiogram (ECG).
Milwaukee's NPR radio program Lake Effect speaks with Ivor Benjamin, MD, Director of the 果冻影院 Cardiovascular Center about the state of cardiovascular research and the national push to train the general population in CPR and the use of automated external defibrillators (AEDs).
Ivor Benjamin, MD, FAHA, FACC
Director, Cardiovascular Center
Professor, Medicine, Physiology, Pharmacology and Toxicology, Cell Biology, Neurobiology and Anatomy, and Surgery
Froedtert & the 果冻影院
ibenjamin@mcw.edu
Dr. Ivor Benjamin is the Director of the Cardiovascular Center, co-director of the NIH T32 Postdoctoral Fellowship in Cardiovascular Sciences and co-leader of the CVC鈥檚 Signature Program in Precision Cardiovascular Medicine. He is a Professor of Medicine, Physiology, Pharmacology & Toxicology, Cell Biology, Neurobiology & Anatomy, and Surgery at the 果冻影院. Dr. Benjamin earned his MD from the Johns Hopkins University School of Medicine, internship and residency in Internal Medicine at Yale University School of Medicine, and received fellowship training in clinical cardiology, molecular cardiology, and molecular biology at Michael Reese Hospital (University of Chicago), Duke University Medical Center, and The University of Texas Southwestern Medical Center at Dallas. A certified specialist and consultant in internal medicine and cardiology, his clinical interests are general cardiology, inheritable heart failure, and myocardial infarction. His research focuses on genes encoding heat shock proteins and oxido-reductive stress response pathways of direct relevance to genetic forms of heart disease, cardiotoxicological science and precision medicine.
An Established Investigator of the American Heart Association, Dr. Benjamin鈥檚 longstanding and distinguished career as a physician scientist has taken him across the country, including 10 years at the University of Utah School of Medicine where he was named the Division Chief of Cardiology and the Christi T. Smith Endowed Chair of Cardiovascular Medicine. He is the recipient of countless honors including the Award of Merit from the American Heart Association, the Daniel Savage Memorial Service Award from the Association of Black Cardiologists, and the prestigious NIH Director's Pioneer Award from the National Heart, Lung, and Blood Institute. He serves as Editor-in-Chief of Cecil Essential of Medicine 9th Edition and has authored over 130 books, book chapters and scientific papers. Dr. Benjamin is a founding member of the Journal of the American Heart Association, and he currently serves on the editorial boards of Circulation and Circulation Research.
Qiang Dai, PhD
Research Associate II
qdai@mcw.edu
Our laboratory has longstanding interests in the role that stress response (HSF/HSP) pathways play in the development, progression, and, ultimately, the prevention of acquired and inheritable cardiac diseases. My studies of genetically engineered mouse models and somatic cell cultures are exploring the mechanisms underlying the effects of genetic, metabolic (e.g., redox), and other perturbations in ischemic cardioprotection and heart failure.
Elizabeth Schibly
Shuping Lai, PhD
Research Associate II
slai@mcw.edu
My research project aims on modeling cardiac diseases in a culture dish by utilizing patient specimens. We are creating cardiomyocytes from human induced pluripotent stem cells, differentiate them into cardiomyocytes and use them as a means to mimic the disease in a dish. My major interests are drug-screenings and biochemical assays to exhibit different susceptibilities of cardiac cells to cardiac drugs, to predict adverse drug responses more accurately and to find best suitable drugs for cardiac diseases.
Recent Publications
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(Elkind MSV, Arnett DK, Benjamin IJ, Eckel RH, Grant AO, Houser SR, Jacobs AK, Jones DW, Robertson RM, Sacco RL, Smith SC Jr, Weisfeldt ML, Wu JC, Jessup M.) Circulation. 2024 Mar 19;149(12):e964-e985 PMID: 38344851 02/12/2024
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(Ibrahim EH, Rubenstein J, Sosa A, Stojanovska J, Pan A, North P, Rui H, Benjamin I.) Tomography. 2024 Feb 27;10(3):331-348 PMID: 38535768 PMCID: PMC10974260 SCOPUS ID: 2-s2.0-85188901578 03/27/2024
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(Jacobs ER, Ross GR, Padilla N, Pan AY, Liegl M, Puzyrenko A, Lai S, Dai Q, Uche N, Rubenstein JC, North PE, Ibrahim EH, Sun Y, Felix JC, Rui H, Benjamin IJ.) J Mol Cell Cardiol. 2023 Dec;185:1-12 PMID: 37839656 PMCID: PMC11000691 SCOPUS ID: 2-s2.0-85174455933 10/16/2023
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(Wallace M, Zahr H, Perati S, Morsink CD, Johnson LE, Gacita AM, Lai S, Wallrath LL, Benjamin IJ, McNally EM, Kirby TJ, Lammerding J.) Mol Biol Cell. 2023 Aug 16;34(12):mbcE21100527 PMID: 37585285 PMCID: PMC10846625 08/16/2023
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(Uche N, Dai Q, Lai S, Kolander K, Thao M, Schibly E, Sendaydiego X, Zielonka J, Benjamin IJ.) Antioxidants (Basel). 2023 Aug 09;12(8) PMID: 37627583 PMCID: PMC10451268 08/26/2023
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(Puzyrenko A, Jacobs ER, Padilla N, Devine A, Aljadah M, Gantner BN, Pan AY, Lai S, Dai Q, Rubenstein JC, North PE, Simpson PM, Willoughby RE, O'Meara CC, Flinn MA, Lough JW, Ibrahim EH, Zheng Z, Sun Y, Felix J, Hunt BC, Ross G, Rui H, Benjamin IJ.) J Am Heart Assoc. 2023 Feb 21;12(4):e027990 PMID: 36789856 PMCID: PMC10111490 SCOPUS ID: 2-s2.0-85148479620 02/16/2023
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(Sanyahumbi A, Ali S, Benjamin IJ, Karthikeyan G, Okello E, Sable CA, Taubert K, Wyber R, Zuhlke L, Carapetis JR, Beaton AZ, American Heart Association.) J Am Heart Assoc. 2022 Mar;11(5):e024517 PMID: 35049336 PMCID: PMC9075066 01/21/2022
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(McNally EM, Elkind MSV, Benjamin IJ, Chung MK, Dillon GH, Hernandez AF, Ibeh C, Lloyd-Jones DM, McCullough LD, Wold LE, Wright DR, Wu JC.) Circulation. 2021 Dec 07;144(23):e461-e471 PMID: 34719260 PMCID: PMC10227717 SCOPUS ID: 2-s2.0-85122546616 11/02/2021
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(Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL.) Redox Biol. 2021 Nov 25;48:102196 PMID: 34872044 PMCID: PMC8646998 12/07/2021
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(Hateley S, Lopez-Izquierdo A, Jou CJ, Cho S, Schraiber JG, Song S, Maguire CT, Torres N, Riedel M, Bowles NE, Arrington CB, Kennedy BJ, Etheridge SP, Lai S, Pribble C, Meyers L, Lundahl D, Byrnes J, Granka JM, Kauffman CA, Lemmon G, Boyden S, Scott Watkins W, Karren MA, Knight S, Brent Muhlestein J, Carlquist JF, Anderson JL, Chahine KG, Shah KU, Ball CA, Benjamin IJ, Yandell M, Tristani-Firouzi M.) Nat Commun. 2021 Nov 08;12(1):6442 PMID: 34750360 PMCID: PMC8575962 11/10/2021
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(Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL.) Redox Biology. December 2021;48 SCOPUS ID: 2-s2.0-85120438753 12/01/2021
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(Dai W, Lund H, Chen Y, Zhang J, Osinski K, Jones SZ, Kreuziger LB, López JA, Benjamin IJ, Silverstein RL, Zheng Z.) J Clin Lipidol. 2021;15(5):724-731 PMID: 34470719 PMCID: PMC8353976 SCOPUS ID: 2-s2.0-85114047849 09/03/2021